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Haptoglobin,HumanPlasma,MixedType

触珠蛋白

ExtinctionCoefficient:1.20

Salt-freelyophilizedsolid.

Storage:-20°C

Anacute-phaseplasmaproteinfoundinhumanplasmaat100-300mgper100ml.Bindshemoglobin,thuspreventinglossofironthroughthekidneys.Humansarepolymorphicforhaptoglobin,withthreemajorphenotypes:Hp1-1,Hp2-1,andHp2-2.Whilethephenotypicdistributioncanvarygreatlybetweenethnicitiesandgeographiclocation,theHp2-1phenotypeisthemostprevalentphenotypeinhumans.PlasmaconcentrationsofhaptoglobinarehighestinindividualswithHp1-1,intermediateinHp2-1individuals,andlowestinHp2-2individuals.Hp1-1isthemosteffectiveatbindinghemoglobin,andHp2-2istheleasteffective.Thisfunctionaldifferencemaybeassociatedwiththefrequencyandseverityofepilepsyattacks,asresearchershavefoundacorrelationbetweenrecurringseizuresandtheHp2-2phenotype.


Purity:>=95%bySDS-PAGE

PreparedfromplasmashowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.

AthensResearch&Technologyproductsarelaboratoryreagentsandarenottobeadministeredtohumansorusedforanydrugpurpose.Forresearchuseonly.



MyeloperoxidaseEnzymeImmunoassayKit

髓过氧化物酶免疫分析试剂盒

HumanMPOEIAKITFEATURES:

USE-MeasurehumanMPOinavarietyofmatrices
SAMPLE-Serum,Platelet-PoorHeparinPlasma,Saliva,UrineorTissueCultureMedia
SAMPLES/KIT-40induplicate
SENSITIVITY-0.068ng/mL
STABILITY-liquidreagentsstableat4°C
QUICKRESULTS-2.5HOURS

Myeloperoxidase(MPO)isatetramericheme-containingproteinabundantlyproducedinneutrophilgranulocyteswhereitplaysanimportantanti-microbialrole.DuringdegranulationMPOisreleasedintotheextracellularspace.There,aspartoftheneutrophils“respiratoryburst”,itproduceshypochlorousacidfromhydrogenperoxideandCl–.MPOalsouseshydrogenperoxidetooxidizetyrosinetothetyrosylradical.Bothhypochlorousacidandtyrosylarecytotoxicandwhenpresentcankillbacteriaandotherpathogens.Hereditarydeficiencyofmyeloperoxidasepredisposesindividualstoimmunedeficiency.

StudieshaveshownanassociationbetweenelevatedMPOlevelsandcoronaryarterydisease,andin2003itwassuggestedthatMPOmayserveasasensitivepredictorofmyocardialinfarctioninpatientscomplainingofchestpain.SincethattimetheclinicalutilityofMPOtestingincardiacpatientshasbeensolidlyestablishedintheliteraturewithwellover100paperspublished.In2010thisclinicalapplicationwasfurtherrefinedbyadditionalstudieswhichdeterminedthatmeasuringbothMPOandC-reactiveprotein(CRP)providedmoreaccuratepredictionofmortalityriskthanmeasuringjustCRPalone.


AthensResearch&Technology公司位于美国乔治亚州雅典市,从1986年以来一直致力于纯化高纯度,高活性的人类蛋白质和开发这些蛋白的多克隆抗血清。我们的常规产品包括丝氨酸蛋白酶、蛋白酶抑制剂、中性粒细胞酶、载脂蛋白、脂蛋白,血小板蛋白、转铁蛋白、免疫球蛋白等。二十年多年来,世界各地的研究人员都在使用我们公司的产品。在炎症、冠状动脉疾病、自身免疫性疾病、癌症、老年痴呆症等等研究的主要科学出版物中都能看到引用我们公司的产品。我们提供优质,可靠的产品和出色的客户服务。我们期待着您的业务。如果需要定制研究服务,AthensResearch&Technology公司能够根据您的项目要求提供无与伦比的试剂。


Myeloperoxidase,HumanNeutrophil

人嗜中性粒细胞髓过氧化物酶

100ug$85

1mg $700

 

MW:130,000-150,000
ExtinctionCoefficient:1.45

Lyophilizedfrom50mMNaacetate,pH6.0with100mMNaCl


Thishemeproteincatalyzesoxidationsbyhydrogenperoxide,includingMPO-chloridemediatedkillingofmicrobesandtumorcells,inactivationofhemotacticfactors,crosslinkingofproteinsandinclinationofproteins.

Activity:180-220unitspermgproteinafterlyophilization.Oneunitisdefinedastheamountofenzymethatdecomposesoneumoleofhydrogenperoxideperminuteat25oC,pH6.0.Reactionmixturecontains30mMsodiumphosphate,pH6.1,30mMguaiacol,and0.0012%(0.35mM)hydrogenperoxide.

Storage:-20°C

Purity:>=95%bySDS-PAGE

PreparedfromwholebloodshowntobenonreactiveforHBsAg,anti-HCV,anti-HBc,andnegativeforanti-HIV1&2byFDAapprovedtests.

AthensResearch&Technologyproductsarelaboratoryreagentsandarenottobeadministeredtohumansorusedforanydrugpurpose.Forresearchorfurthermanufacturinguseonly.




AthensResearchX品牌历史介绍:苏州蚂蚁淘生物科技有限公司,作为一家生命科学领域的高科技生物公司,目前代理销售二十多家欧美著名生物技术公司的产品,覆盖了免疫学、细胞生物学、分子生物学、药物筛选、生物制药、食品检测、疫苗生产等领域。